盛南(Sheng Nan)
長聘教軌副教授
Email: shengnan@sjtu.edu.cn

研究方向

1. ? ? ?新型環(huán)境污染物的危害識別和高通量篩查

2. ? ? ?新型環(huán)境污染物毒性效應(yīng)的分子機(jī)制研究

3. ? ? ?環(huán)境污染物與生物大分子的相互作用及其生物毒性效應(yīng)

個(gè)人簡歷

????2018年于中國科學(xué)院動(dòng)物研究所獲得理學(xué)博士學(xué)位;2018-2020年,于中國科學(xué)院動(dòng)物研究所開展博士后研究,研究工作包括:新型多氟及全氟烷基化合物對小鼠的肝臟毒性及機(jī)制、多氟及全氟化合物與關(guān)鍵生物大分子間的相互作用。

????2020年至今,上海交通大學(xué)環(huán)境科學(xué)與工程學(xué)院,長聘教軌助理教授

代表性論著

1.?????? Sheng N, Wang J, Guo Y, Wang J and Dai J. Interactions of perfluorooctanesulfonate (PFOS) and 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) with human serum albumin (HSA): A comparative study [J]. Chemical Research in Toxicology. 2020, 33(6): 1478-1486.

2.?????? Sheng N, Pan Y, Guo Y, Sun Y and Dai J. Hepatotoxic effects of hexafluoropropylene oxide trimer acid (HFPO-TA), a novel perfluorooctanoic acid (PFOA) alternative, on mice at low dosage exposure[J]. Environmental Science & Technology. 2018, 52(14):8005-8015.

3.?????? Sheng N, Cui R, Wang J, Guo Y, Wang J and Dai J. Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein[J]. Archives of Toxicology. 2018, 92(1):359-369.高被引論文

4.?????? Sheng N, Zhou X, Zheng F, Pan Y, Guo X, Guo Y, Sun Y and Dai J. Comparative hepatotoxicity of 6:2 fluorotelomer carboxylic acid and 6:2 fluorotelomer sulfonic acid, two fluorinated alternatives to long-chain perfluoroalkyl acids, on adult male mice[J]. Archives of Toxicology. 2017, 91(8):2909-2919.

5.?????? Sheng N, Li J, Liu H, Zhang A and Dai J. Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein[J]. Archives of Toxicology. 2016, 90(1):217-27.

6.?????? Zhang W1, Sheng N1, Wang M, Zhang H and Dai J. Zebrafish reproductive toxicity induced by chronic perfluorononanoate exposure[J]. Aquatic Toxicology. 2016, 175:269-76.

研究成果

1. 基于分子與蛋白相互作用的新型全氟聚醚羧酸在小鼠體內(nèi)分布機(jī)制研究 (青年科學(xué)基金項(xiàng)目: 21906160)

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